Microbial Bioactives
Microbial Bioactives | Online ISSN 2209-2161
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Volume 9 Number 1 2026
REVIEWS (Open Access)
Blockchain-Based Traceability as a Foundational Enabler of Trust, Safety, and Sustainability in Modern Production Systems: A Systematic Review and Meta-Analytical Synthesis
Lahcen Hassani 1, Marcello Iriti 2, Sara Vitalini 2, Chaima Alaoui Jamali 3, Ayoub Kasrati 4, Ahmed Nafis 5
Microbial Bioactives 9 (1) 1-8 https://doi.org/10.25163/microbbioacts.9110622
Submitted: 02 January 2026 Revised: 25 February 2026 Accepted: 05 March 2026 Published: 07 March 2026
Abstract
Modern production systems across agriculture, biomedicine, materials science, and engineering are increasingly challenged by fragmented supply chains, declining consumer trust, environmental pressures, and recurring safety failures. These challenges have intensified the demand for transparent, reliable, and sustainable frameworks capable of ensuring product integrity across complex value chains. Drawing on evidence synthesized from systematic reviews and meta-analytical studies, this work situates blockchain-based traceability (BBT) within a broader interdisciplinary landscape that includes food safety governance, natural bioactive compound research, sustainable material development, and bio-inspired design methodologies. In the agricultural sector, repeated food safety crises and the limitations of centralized traceability systems have exposed critical gaps in transparency, data integrity, and rapid response capability. Blockchain technology, characterized by decentralization, immutability, and shared consensus, has emerged as a promising infrastructure to address these deficiencies by enabling end-to-end, tamper-resistant traceability. Parallel challenges in pharmaceutical and nutraceutical research—particularly concerning the sourcing, reproducibility, and safety of natural compounds—further underscore the importance of verifiable data systems. Similarly, sustainability-driven industries such as smart textiles and advanced materials face growing scrutiny over unverifiable environmental claims and lifecycle impacts, reinforcing the need for trusted data governance. Bio-inspired design approaches complement these technological advances by offering systematic, data-driven methods for integrating performance, resilience, and environmental harmony. Collectively, the evidence highlights blockchain-based traceability not as an isolated technological intervention but as a foundational enabler of trust, accountability, and sustainability across diverse sectors. This synthesis provides a conceptual basis for evaluating BBT through systematic review and meta-analysis, supporting its role in future intelligent and sustainable production systems.
Keywords: Blockchain-based traceability; food safety; supply chain transparency; sustainability; bioactive compounds; biomimetic design; systematic review; meta-analysis
References
Atanasov, A. G., Waltenberger, B., Pferschy-Wenzig, E.-M., Linder, T., Wawrosch, C., Uhrin, P., … Stuppner, H. (2015). Discovery and resupply of pharmacologically active plant-derived natural products: A review. Biotechnology Advances, 33(8), 1582–1614. https://doi.org/10.1016/j.biotechadv.2015.08.001
Aung, M. M., & Chang, Y. S. (2014). Traceability in a food supply chain: Safety and quality perspectives. Food Control, 39, 172–184. https://doi.org/10.1016/j.foodcont.2013.11.007
Beulens, A. J. M., Broens, D. F., Folstar, P., & Hofstede, G. J. (2005). Food safety and transparency in food chains and networks. Trends in Food Science & Technology, 16(10), 481–489.
Bi, X., Zhang, Y., Liu, Z., & Wang, H. (2023). Bionic design methodology for disaster-prevention structures. Engineering Structures, 275, 115230. https://doi.org/10.1016/j.engstruct.2022.115230
Booker, A., Frommenwiler, D., Reich, E., Horsfield, S., & Heinrich, M. (2018). Adulteration and poor quality of herbal medicines: A review of causes, consequences, and solutions. Frontiers in Pharmacology, 9, 134.
Bosona, T., & Gebresenbet, G. (2013). Food traceability as an integral part of logistics management in food and agricultural supply chain. Food Control, 33(1), 32–48. https://doi.org/10.1016/j.foodcont.2013.02.004
Brundtland Commission. (1987). Our common future. Oxford University Press.
Casino, F., Dasaklis, T. K., & Patsakis, C. (2019). A systematic literature review of blockchain-based applications: Current status, classification, and open issues. Telecommunications Systems, 71(4), 401–423.
Delmas, M. A., & Burbano, V. C. (2011). The drivers of greenwashing. California Management Review, 54(1), 64–87. https://doi.org/10.1525/cmr.2011.54.1.64
Golan, E., Krissoff, B., Kuchler, F., Calvin, L., Nelson, K., & Price, G. (2004). Traceability in the U.S. food supply: Economic theory and industry studies. Economic Research Service, USDA.
Hobbs, J. E. (2004). Information asymmetry and the role of traceability systems. American Journal of Agricultural Economics, 86(3), 675–684.
Kamble, S. S., Gunasekaran, A., & Arha, H. (2020). Understanding the blockchain technology adoption in supply chains. International Journal of Production Research, 58(7), 2082–2097.
Kelepouris, T., Pramatari, K., & Doukidis, G. (2007). RFID-enabled traceability in the food supply chain. Industrial Management & Data Systems, 107(2), 183–200. https://doi.org/10.1108/02635570710723804
Khan, S., Ullah, F., & Mahmood, T. (2023). Proteomic insights into phytochemicals and their biological mechanisms. Journal of Proteomics, 274, 104802.
Konstantinou, F., et al. (2025). Thyroid hormone receptor modulation and metabolic outcomes. Metabolism, 146, 155661.
Kouhizadeh, M., Sarkis, J., & Zhu, Q. (2021). At the nexus of blockchain technology, sustainability, and supply chain management. International Journal of Production Economics, 231, 107831. https://doi.org/10.1016/j.ijpe.2020.107831
Li, Y., Kong, D., Fu, Y., Sussman, M. R., & Wu, H. (2020). The effect of natural products on metabolic disease. Pharmacological Research, 160, 105074. https://doi.org/10.1016/j.phrs.2020.105074
Li, Z., Wang, Y., & Guo, M. (2022). Sustainability challenges and innovations in smart textiles. Journal of Cleaner Production, 348, 131267. https://doi.org/10.1016/j.jclepro.2022.131267
Lv, G., Xu, Z., & Zhang, Y. (2023). Blockchain-based traceability systems in agriculture: A systematic review. Agriculture, 13(9), 1757. https://doi.org/10.3390/agriculture13091757
Niinimäki, K., Peters, G., Dahlbo, H., Perry, P., Rissanen, T., & Gwilt, A. (2020). The environmental price of fast fashion. Nature Reviews Earth & Environment, 1, 189–200. https://doi.org/10.1038/s43017-020-0039-9
Porter, M. E., & Kramer, M. R. (2019). Creating shared value. Harvard Business Review, 97(1), 42–55.
Queiroz, M. M., Telles, R., & Bonilla, S. H. (2020). Blockchain adoption in supply chains. International Journal of Production Economics, 222, 107518.
Raja Santhi, A., & Muthuswamy, P. (2022). Industrial transparency and sustainable manufacturing. Sustainable Production and Consumption, 30, 567–578.
Regattieri, A., Gamberi, M., & Manzini, R. (2007). Traceability of food products: General framework and experimental evidence. Journal of Food Engineering, 79(2), 409–417.
Saaty, T. L. (2008). Decision making with the analytic hierarchy process. International Journal of Services Sciences, 1(1), 83–98. https://doi.org/10.1504/IJSSCI.2008.017590
Saberi, S., Kouhizadeh, M., Sarkis, J., & Shen, L. (2019). Blockchain technology and its relationships to sustainable supply chain management. International Journal of Production Research, 57(7), 2117–2135. https://doi.org/10.1080/00207543.2018.1533261
Sinha, R. A., Singh, B. K., & Yen, P. M. (2019). Thyroid hormones and metabolism. Endocrine Reviews, 40(2), 476–522.
Thomas, G., Font, X., & Higham, J. (2023). Greenwashing, governance, and sustainable business practice. Business Strategy and the Environment, 32(4), 1901–1915.
Van Rijswijk, W., & Frewer, L. J. (2012). Consumer trust in food supply chains. Food Policy, 37(3), 231–245.
Verbeke, W., Ward, R. W., & Viaene, J. (2007). Consumer trust in food safety after food crises. Journal of Economic Psychology, 28(6), 689–704.
Vincent, J. F. V., Bogatyreva, O. A., Bogatyrev, N. R., Bowyer, A., & Pahl, A.-K. (2006). Biomimetics: Its practice and theory. Journal of the Royal Society Interface, 3(9), 471–482. https://doi.org/10.1098/rsif.2006.0127
Williamson, G. (2017). The role of polyphenols in modern nutrition. British Journal of Nutrition, 118(6), 553–567.
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