Advancing Cancer Imaging with Artificial Intelligence Clinical Application and Challenges
Md Nazmul Alam Bhuiyan1*, Rabi Sankar Mondal1, Lamia Akter2
Journal of Primeasia 6(1) 1-8 https://doi.org/10.25163/primeasia.6110322
Submitted: 25 May 2025 Revised: 11 August 2025 Published: 12 August 2025
Abstract
Artificial intelligence (AI) is transforming cancer imaging in remarkable ways. It is not just improving how accurately we can diagnose cancer; it is also speeding up processes in clinical settings and helping to tailor treatments specifically for each patient. With the help of advanced algorithms, such as machine learning and deep learning, AI can identify subtle patterns in medical images that the human eye may overlook. This capability enables earlier and more precise cancer detection using various imaging techniques, including CT scans, MRIs, PET scans, and ultrasounds. In exploring how AI is being used in clinical practice, we also need to consider the advantages it brings, such as increased diagnostic accuracy and efficiency, as well as potential cost savings. However, there are real challenges to its widespread use in healthcare. We also need to consider how to effectively communicate AI’s decisions to doctors and patients, and ensure that healthcare professionals receive the necessary training and support to utilize these tools effectively. There are exciting avenues to explore in AI development, such as federated learning and enhancing the transparency and understandability of AI systems. Collaborating across different fields will be crucial to the safe and effective implementation of AI in healthcare. The promise of AI can help bridge gaps in diagnostic access, particularly in regions lacking healthcare resources, making it a valuable ally in the fight against global healthcare inequalities. Ultimately, AI is not about replacing healthcare professionals; it is about partnering with them to enhance cancer diagnosis and treatment, ultimately leading to better patient outcomes.
Keywords: Artificial Intelligence, Cancer Imaging, Machine Learning, Radiomics, Precision Medicine.
References
Anaby, D., Shavin, D., Zimmerman-Moreno, G., Nissan, N., Friedman, E., & Sklair-Levy, M. (2023). ‘Earlier than early’ detection of breast cancer in Israeli BRCA mutation carriers applying AI-based analysis to consecutive MRI scans. Cancers, 15(11), 3120. https://doi.org/10.3390/cancers15113120
Bayareh-Mancilla, R., Medina-Ramos, L., Toriz-Vázquez, A., Hernández-Rodríguez, Y., & Cigarroa-Mayorga, O. (2023). Automated computer-assisted medical decision-making system based on morphological shape and skin thickness analysis for asymmetry detection in mammographic images. Diagnostics, 13(20), 3440. https://doi.org/10.3390/diagnostics13203440
Buser, M., van der Steeg, A., Wijnen, M., Fitski, M., van Tinteren, H., van den Heuvel-Eibrink, M., Littooij, A., & van der Velden, B. (2023). Radiologic versus segmentation measurements to quantify Wilms tumor volume on MRI in pediatric patients. Cancers, 15(8), 2115. https://doi.org/10.3390/cancers15082115
Cozzi, A., Cè, M., De Padova, G., Libri, D., Caldarelli, N., Zucconi, F., Oliva, G., & Cellina, M. (2023). Deep learning-based versus iterative image reconstruction for unenhanced brain CT: A quantitative comparison of image quality. Tomography, 9(4), 1629–1637. https://doi.org/10.3390/tomography9040123
Farahat, Z., Zrira, N., Souissi, N., Benamar, S., Belmekki, M., Ngote, M., & Megdiche, K. (2023). Application of deep learning methods in a Moroccan ophthalmic center: Analysis and discussion. Diagnostics, 13(10), 1694. https://doi.org/10.3390/diagnostics13101694
Gibala, S., Obuchowicz, R., Lasek, J., Schneider, Z., Piorkowski, A., Pociask, E., & Nurzynska, K. (2023). Textural features of MR images correlate with an increased risk of clinically significant cancer in patients with high PSA levels. Journal of Clinical Medicine, 12(9), 2836. https://doi.org/10.3390/jcm12092836
Huang, C., Chiang, H., Hsieh, C., Chou, C., Jhou, Z., Hou, T., & Shaw, J. (2023). Using a deep-learning-based artificial intelligence technique to automatically evaluate the collateral status of multiphase CTA in acute ischemic stroke. Tomography, 9(2), 647–656. https://doi.org/10.3390/tomography9020049
Hunter, B., Hindocha, S., & Lee, Richard. (2022). The Role of Artificial Intelligence in Early Cancer Diagnosis. Cancers. 14. 10.3390/cancers14061524.
Jeong, D., Jeong, W., Lee, J., & Park, S. (2023). Use of automated machine learning for classifying hemoperitoneum on ultrasonographic images of Morrison’s pouch: A multicenter retrospective study. Journal of Clinical Medicine, 12(12), 4043. https://doi.org/10.3390/jcm12124043
Kim, S., & Kim, Y. (2023). Effects of path-finding algorithms on the labeling of the centerlines of Circle of Willis arteries. Tomography, 9(5), 1423–1433. https://doi.org/10.3390/tomography9050109
Kode, H., & Barkana, B. (2023). Deep learning- and expert knowledge-based feature extraction and performance evaluation in breast histopathology images. Cancers, 15(11), 3075. https://doi.org/10.3390/cancers15113075
Kufel, J., Bargiel-Laczek, K., Kozlik, M., Czogalik, L., Dudek, P., Magiera, M., Bartnikowska, W., Lis, A., Paszkiewicz, I., Kocot, S., et al. (2023). Chest X-ray foreign objects detection using artificial intelligence. Journal of Clinical Medicine, 12(17), 5841. https://doi.org/10.3390/jcm12175841
Kukla, P., Maciejewska, K., Strojna, I., Zapal, M., Zwierzchowski, G., & Bak, B. (2023). Extended reality in diagnostic imaging—A literature review. Tomography, 9(5), 1071–1082. https://doi.org/10.3390/tomography9050087
Lien, W., Yeh, C., Chang, C., Chang, C., Wang, W., Chen, C., & Lin, Y. (2023). Convolutional neural networks to classify Alzheimer’s disease severity based on SPECT images: A comparative study. Journal of Clinical Medicine, 12(7), 2218. https://doi.org/10.3390/jcm12072218
Lindemann, M., Glänzer, L., Roeth, A., Schmitz-Rode, T., & Slabu, I. (2023). Towards realistic 3D models of tumor vascular networks. Cancers, 15(20), 5352. https://doi.org/10.3390/cancers15205352
Ma, H., Xu, C., Nie, C., Han, J., Li, Y., & Liu, C. (2023). DBE-Net: Dual boundary-guided attention exploration network for polyp segmentation. Diagnostics, 13(5), 896. https://doi.org/10.3390/diagnostics13050896
Mayerhoefer, M. E., Materka, A., Langs, G., Häggström, I., Szczypinski, P., Gibbs, P., & Cook, G. (2020). Introduction to radiomics. Journal of Nuclear Medicine, 61(4), 488–495. https://doi.org/10.2967/jnumed.118.222893
Mendes, J., Matela, N., & Garcia, N. (2023). Avoiding tissue overlap in 2D images: Single-slice DBT classification using convolutional neural networks. Tomography, 9(2), 398–412. https://doi.org/10.3390/tomography9020033
Nadkarni, R., Clark, D., Allphin, A., & Badea, C. (2023). A deep learning approach for rapid and generalizable denoising of photon-counting micro-CT images. Tomography, 9(6), 1286–1302. https://doi.org/10.3390/tomography9060114
Najjar, R. (2023). Redefining radiology: A review of artificial intelligence integration in medical imaging. Diagnostics, 13(14), 2760. https://doi.org/10.3390/diagnostics13142760
Nam, H., Park, S., Ho, J., Park, S., Cho, J., & Lee, Y. (2023). A key-point detection algorithm in deep learning can predict lower limb alignment using simple knee radiographs. Journal of Clinical Medicine, 12(5), 1455. https://doi.org/10.3390/jcm12051455
Obuchowicz, R., Kruszynska, J., & Strzelecki, M. (2021). Classifying median nerves in carpal tunnel syndrome: Ultrasound image analysis. Biocybernetics and Biomedical Engineering, 41(1), 335–351. https://doi.org/10.1016/j.bbe.2020.11.003
Ozga, J., Wyka, M., Raczko, A., Tabor, Z., Oleniacz, Z., Korman, M., & Wojciechowski, W. (2023). Performance of a fully automated algorithm detecting bone marrow edema in sacroiliac joints. Journal of Clinical Medicine, 12(14), 4852. https://doi.org/10.3390/jcm12144852
Ozkara, B., Chen, M., Federau, C., Karabacak, M., Briere, T., Li, J., & Wintermark, M. (2023). Deep learning for detecting brain metastases on MRI: A systematic review and meta-analysis. Cancers, 15(2), 334. https://doi.org/10.3390/cancers15020334
Peretti, L., Donatelli, G., Cencini, M., Cecchi, P., Buonincontri, G., Cosottini, M., Tosetti, M., & Costagli, M. (2023). Generating synthetic radiological images with PySynthMRI: An open-source cross-platform tool. Tomography, 9(5), 1723–1733. https://doi.org/10.3390/tomography9050136
Piórkowski, A., Obuchowicz, R., Urbanik, A., & Strzelecki, M. (2023). Advances in musculoskeletal imaging and their applications. Journal of Clinical Medicine, 12(21), 6585. https://doi.org/10.3390/jcm12216585
Poel, R., Kamath, A., Willmann, J., Andratschke, N., Ermis, E., Aebersold, D., Manser, P., & Reyes, M. (2023). Deep-learning-based dose predictor for glioblastoma—Assessing the sensitivity and robustness for dose awareness in contouring. Cancers, 15(16), 4226. https://doi.org/10.3390/cancers15164226
Pula, M., Kucharczyk, E., Zdanowicz, A., & Guzinski, M. (2023). Image quality improvement in deep learning image reconstruction of head computed tomography examination. Tomography, 9(6), 1485–1493. https://doi.org/10.3390/tomography9060120
Qiu, H., Ding, S., Liu, J., Wang, L., & Wang, X. (2022). Applications of Artificial Intelligence in Screening, Diagnosis, Treatment, and Prognosis of Colorectal Cancer. Current Oncology, 29(3), 1773-1795. https://doi.org/10.3390/curroncol29030146
Rahmanuddin, S., Jamil, A., Chaudhry, A., Seto, T., Brase, J., Motarjem, P., Khan, M., Tomasetti, C., Farwa, U., Boswell, W., et al. (2023). COVID and cancer: A complete 3D advanced radiological CT-based analysis to predict the outcome. Cancers, 15(3), 651. https://doi.org/10.3390/cancers15030651
Raspe, J., Harder, F., Rupp, S., McTavish, S., Peeters, J., Weiss, K., Makowski, M., Braren, R., Karampinos, D., & Van, A. (2023). Retrospective motion artifact reduction by spatial scaling of liver diffusion-weighted images. Tomography, 9(6), 1839–1856. https://doi.org/10.3390/tomography9060153
Rodrigues, N., Silva, S., Vanneschi, L., & Papanikolaou, N. (2023). A comparative study of automated deep learning segmentation models for prostate MRI. Cancers, 15(6), 1467. https://doi.org/10.3390/cancers15061467
Shanmugam, K., & Rajaguru, H. (2023). Exploration and enhancement of classifiers in the detection of lung cancer from histopathological images. Diagnostics, 13(13), 3289. https://doi.org/10.3390/diagnostics13133289
Siddique, M. A. B., Debnath, A., Nath, N. D., Biswash, M. A. R., & Tufael. (2018). Advancing medical science through nanobiotechnology: Prospects, applications, and future directions. Journal of Primeasia, 1(1), 1–7.
Song, G., Xie, Z., Wang, H., Li, S., Yao, D., Chen, S., & Shi, Y. (2023). Segmentation of the portal vein in multiphase CTA images based on unsupervised domain transfer and pseudo-label. Diagnostics, 13(15), 2250. https://doi.org/10.3390/diagnostics13152250
Strzelecki, M., & Badura, P. (2022). Machine learning for biomedical applications. Applied Sciences, 12(1), 2022. https://doi.org/10.3390/app12012022
Tufael, & Sunny, A. R. (2022). Transforming healthcare with artificial intelligence: Innovations, applications, and future challenges. Journal of Primeasia, 3(1), 1–6.
Tufael, A. R. S., Jamil, A., Alam, M., & Sunny, A. R. (2023). Artificial intelligence in addressing cost, efficiency, and access challenges in healthcare. Journal of Primeasia, 4(1), 1–5.
Yang, D., Huang, Y., Li, B., Cai, J., & Ren, G. (2023). Dynamic chest radiograph simulation technique with deep convolutional neural networks: A proof-of-concept study. Cancers, 15(21), 5768. https://doi.org/10.3390/cancers15215768
Zhang, Y., Wu, C., Xiao, Z., Lv, F., & Liu, Y. (2023). A deep learning radiomics nomogram to predict response to neoadjuvant chemotherapy for locally advanced cervical cancer: A two-center study. Diagnostics, 13(5), 1073. https://doi.org/10.3390/diagnostics13051073
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